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AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM

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Buy AM-2201 online. AM-2201 is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.

AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively.

This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. For a representative CofA please contact our technical support.

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ynonyms:AM-2201 (AM 2201;[1-(5-fluoropentyl)-1H-indole-3-yl](naphthalene-1-yl)methanone;AM-2201 (1-[(5-fluoropentyl)-1H-indol-3-yl]-(naphthalen-1-yl)methanone);1-(5-Fluoropentyl)-3-(1-naphthoyl)-1H-indole;1-(5-fluoropentyl)-3-[(naphthalen-1-yl)carbonyl]-1H-indole;(1-(5-Fluoropentyl)-3-(naphthalen-1-oyl)indole);(1-(5-fluoropentyl)-1H-indol-3-yl)(naphthalen-1-yl)Methanone;1-(5-fluoropentyl)-3-(naphtalen-1-oy)indole.

Product Description

Cas No: 335161-24-5
Formula: C24H22FNO
IUPAC: 1-[(5-fluoropentyl)-1H-indol-3-yl]-(naphthalen-1-yl) methanone

Buy AM-2201 crystal
Buy AM-2201 crystal AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor. It is part of the AM series of cannabinoids discovered by Alexandros Makriyannis at Northeastern University.
AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a Ki of 1.0 nM at CB1 and 2.6 nM at CB2. The 4-methyl functional analog MAM-2201 probably has similar affinities. AM-2201 has an EC50 of 38 nM for human CB1 receptors, and 58 nM for human CB2 receptors. AM-2201 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity.

Product Description

AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid.

AM2201 is regulated as a Schedule I compound in the United States.

Abstract

Novel synthetic cannabinoids are appearing in recreational drug markets worldwide. Pharmacological characterization of these new drugs is needed to inform clinicians, toxicologists, and policy makers who monitor public health. [1-(5-Fluoropentyl)-1H-indol-3-yl]

The identification was based on liquid chromatography–mass spectrometry (LC–MS) and gas chromatography–mass spectrometry (GC–MS), high-resolution MS, and nuclear magnetic resonance analyses. Different from the representative synthetic cannabinoids, such as JWH-018, which have a naphthoylindole moiety, compounds 1 and 2 were completely new.

Precautions

All of Croweed Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to Croweed that you will properly test and use any Products purchased from Croweed in accordance with industry standards. Croweed and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. Croweed reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to Croweed within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Technical Information

Formal Name: [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone
CAS Number: 335161-24-5
Molecular Formula: C24H22FNO
Formula Weight: 359.4
Purity: ?98%
Formulation: A neat solid
?max: 218, 247, 315 nm
SMILES: O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCCF)C4=CC=CC=C43
InChi Code: InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

Quantity Per Order

10 Grams, 20 Grams, 50Grams, 100 Grams, 500 Grams

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